There are two ways of doing this:
- Make the users local admins and lockdown the workstations using Group Policies
- Don't make the users local admins but then you have to find out by trial and error to what registry hives and folders needs specific permissions. You can use FileMon and Regmon to figure out what such application needs.
I always prefer option 1. because it is much easier to controll and it is centralized. If you opt for option 2 you will need to set permissions on each workstation manually or script the stuff. Not a nice task if the application provider decides that with an update of the application everything is changed...
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